Bret L. Judson
Cell biology
My interests lie in the field of cell biology with particular emphasis on using microscopy-based approaches to solve questions. I have been broadly trained in various light- and electron-based microscopies.
For my graduate work, I used a combination of light and electron microscopy (both SEM and TEM) to solve ultrastructural details in the coralline red alga Jania adhaerens. working in the laboratory of Curt Pueschel.
As a research associate at Upstate Medical University in Syracuse, NY, I worked in the laboratory of Jerrold Abraham, the Director of Environmental and Occupational Pathology and Andrew Hunt, a research associate professor. I used a variety of techniques (light and electron microscopy) to characterize the particulate matter in lung tissue from Londoners who died at the time of the catastrophic smog event of December 1952.
After completion of the work in Syracuse, I took a position in the laboratory of William Brown in the department of Molecular Biology and Genetics at Cornell University in Ithaca, NY. I was responsible for managing all aspects of the departmental TEM and a multi-user confocal microscope as well as having research responsibilities in Dr. Brown´s lab. In my own research, I used a variety of techniques to study the secretory and endocytic membrane trafficking pathways. In particular, my work relied heavily on live cell spinning disk confocal microscopy. Additionally, I used wide-field fluorescence and transmission electron microscopy to study the same events.
Currently, at Arizona State University, I manage the W.M. Keck Bioimaging Laboratory and I also teach the Advanced Bioimaging Laboratory course Bio598L.
Selected Publications
Chambers K, Judson B, Brown WJ A unique lysophospholipid acyltransferase (LPAT) antagonist, CI-976, affects secretory and endocytic membrane trafficking pathways Journal of Cell Science 118 (14): 3061-3071 Jul 15 2005
Pueschel CM, Judson BL, Wegeberg S Decalcification during epithallial cell turnover in Jania adhaerens (Corallinales, Rhodophyta) Phycologia 44 (2): 156-162 Mar 2005
Chan D, Strang M, Judson B, Brown WJ Inhibition of membrane tubule formation and trafficking by isotetrandrine, an antagonist of G-protein-regulated phospholipase A(2) enzymes Molecular Biology of the Cell 15 (4): 1871-1880 Apr 2004
Hunt A, Abraham JL, Judson B, Berry CL Toxicologic and epidemiologic clues from the characterization of the 1952 London smog fine particulate matter in archival autopsy lung tissues Environmental Health Perspectives 111 (9): 1209-1214 Jul 2003
Judson BL, Pueschel CM Ultrastructure of trichocyte (hair cell) complexes in Jania adhaerens (Corallinales, Rhodophyta) Phycologia 41 (1): 68-78 Jan 2002
Pueschel CM, Judson BL, Esken JE, Beiter EL A developmental explanation for the Corallina- and Jania-types of surfaces in articulated coralline red algae (Corallinales, Rhodophyta) Phycologia 41 (1): 79-86 Jan 2002