Carolyn Compton

School of Life Sciences, LSC 278
427 E Tyler Mall
Tempe
Professor
Faculty
TEMPE Campus
Mailcode
4501

Biography

Dr. Carolyn Compton is an academic pathologist specializing in gastrointestinal disease and is board certified in both anatomic and clinical pathology. She is a professor of Life Sciences at Arizona State University and a professor of laboratory medicine and pathology at the Mayo Clinic. She is also an adjunct professor of pathology at both the University of Arizona and Johns Hopkins University. She is the Chief Medical Officer of the National Biomarkers Development Alliance, a member of the Biodesign Institute at ASU, and the Chief Medical Officer of the Complex Adaptive Systems Institute. She is a former professor of pathology at Harvard Medical School, chief of Gastrointestinal Pathology at Massachusetts General Hospital and pathologist-in-chief of the Boston Shriners Children’s Hospital. More recently she has served as the CEO and president of the Critical Path Institute (2012), the director of Biorepositories and Biospecimen Research and the Innovative Molecular Analysis Technologies program at the National Cancer Institute (2005-2011), and the Strathcona Professor and chair of the Department of Pathology at McGill University and pathologist-in-chief of the McGill University Health Center (2000-2005). She is a past chair of the Cancer Committee of the College of American Pathologists and the immediate past chair of the American Joint Committee on Cancer (AJCC). Currently, she is the chair of the Precision Medicine Core of the AJCC and chair of the Pre-analytics for Precision Medicine Project Team at the College of American Pathologists. She has authored more than 500 scientific manuscripts, review articles, books and chapters.

Education

  • Ph.D..Harvard Graduate School of Arts & Sciences 1977
  • M.D. Harvard Medical School 1977
  • B.A. Bryn Mawr College 1969

Google Scholar

Research Interests

extracellular vesicles, preanalytics, colon cancer, medical prediction, cancer staging, biomarker development

Research Group

Multiplexed in-solution serological test for SARS-CoV-2, human coronaviruses and other respiratory pathogens
Self-actualized Biopsy Integrity Management System Ensuring Pathological Accuracy

Publications

  • GTEx Consortium. The genotype-Tissue Expression (GTEx) Project. NatGenetics 2013;45:580-5.
  • Goldman M, Compton C, Mittleman BB. Public-private Partnerships as Driving Forces in the Quest for Innovative Medicines. Clin Transl Med 2013;2:2.
  • Mucci NR, Moore HM, Brigham LE, Goldthwaite CA, Little AR, Lockhart NC, Scott MP, Struewing JP, Vincent Sl, Compton CC, for the cancer Human Biobank (caHUB). Acquisition of Normal Tissue Subgroup, National Cancer Institute Biopreservation and Biobanking. 2013 Apr;11:77-82.
  • Hayes DF, Allen J, Compton C, Gustavsen G, Leonard DGB, McCormack R, Newcomer L, Pothier K, Ransohof D, Schilsky RL, Sigal E, Taube SE, Tunis SR. Breaking a Vicious cycle. Science Transl Med 2013;5:1-7.
  • Warren RS, Atreya CE, Niedzwiecki D, Weinberg V, Donner DB, Mayer RJ, Goldberg RM, Compton C, Zuraek MB, Ye X, Saltz LB, Bertagnolli MM. Association of TP53 Mutational Status and Gender with Survival After Adjuvant Treatment for Stage III Colon Cancer: Results of CALGB 89803. Clin Cancer Research 2013 Epub ahead of print.
  • Compton CC, Byrd DR, Garcia-Aguilar J, Kurtzman SH, Olawaiye A, Washington MK (eds). AJCC Staging Atlas. 2nd Edition. A Companion to the seventh Editions of the AJCC Staging Manual and Handbook.. New York, Springer, 2012.

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  • 243. Webber C, Gospodarowicz M, Sobin LH, Greene FL, Masson MD, Compton C, Brierley J, Groome PA. Improving the TNM classification: Findings from a 10-year continuous literature review. Int J Cancer (2014).
  • 244. Barker AD, Compton CC, Poste G. The National Biomarker Development Alliance accelerating the translation of biomarkers to the clinic. Biomark Med (2014).
  • 245. David KA, Unger FT, Uhlig P, Juhl H, Moore HM, Compton C, Nashan B, Dörner A, de Weerth A, Zornig C. Surgical procedures and postsurgical tissue processing significantly affect expression of genes and EGFR-pathway proteins in colorectal cancer tissue. Oncotarget (2014).
  • Webber C, Gospodarowicz M, Sobin LH, Wittekind C, Greene FL, Mason MD, Compton C, Brierley J, and Groome PA. Improving the TNM classification: findings from a 10-year continuous literature review. Int J Cancer (2014).
  • Goldman M, Compton C, Mittleman BB. Public-private Partnerships as Driving Forces in the Quest for Innovative Medicines. Clin Transl Med (2013).
  • Groelz D, Sobin L, Branton P, Compton C, Wyrich R, Rainen L. Non-formalin fixative versus formalin-fixed tissue: A comparison of histology and RNA quality. Exp Mol Pathol (2013).
  • GTEx Consortium. The genotype-Tissue Expression (GTEx) Project. Nat Genetics (2013).
  • Hayes DF, Allen J, Compton C, Gustavsen G, Leonard DGB, McCormack R, Newcomer L, Pothier K, Ransohof D, Schilsky RL, Sigal E, Taube SE, Tunis SR. Breaking a Vicious Cycle. Transl Med (2013).
  • Mucci NR, Moore HM, Brigham LE, Goldthwaite CA, Little AR, Lockhart NC, Scott MP, Struewing JP, Vincent Sl, Compton CC, for the cancer Human Biobank (caHUB). Acquisition of Normal Tissue Subgroup, National Cancer Institute. Biopreservation and Biobanking (2013).
  • Warren RS, Atreya CE, Niedzwiecki D, Weinberg V, Donner DB, Mayer RJ, Goldberg RM, Compton C, Zuraek MB, Ye X, Saltz LB, Bertagnolli MM. Association of TP53 Mutational Status and Gender with Survival After Adjuvant Treatment for Stage III Colon Cancer: Results of CALGB 89803. Clin Cancer Research (2013).

Courses

Fall 2021
Course Number Course Title
BIO 302 Cancer-Mother of All Diseases
BIO 394 Special Topics
BIO 492 Honors Directed Study
BIO 494 Special Topics
BIO 495 Undergraduate Research
Spring 2021
Course Number Course Title
BIO 302 Cancer-Mother of All Diseases
BIO 394 Special Topics
BIO 492 Honors Directed Study
BIO 493 Honors Thesis
HON 493 Honors Thesis
BIO 494 Special Topics
Fall 2020
Course Number Course Title
BIO 302 Cancer-Mother of All Diseases
BIO 492 Honors Directed Study
HON 492 Honors Directed Study
BIO 494 Special Topics
BIO 495 Undergraduate Research
Spring 2020
Course Number Course Title
BIO 302 Cancer-Mother of All Diseases
BIO 394 Special Topics
BIO 492 Honors Directed Study
BIO 493 Honors Thesis
BIO 494 Special Topics
BIO 495 Undergraduate Research
BIO 499 Individualized Instruction
Fall 2019
Course Number Course Title
BIO 302 Cancer-Mother of All Diseases
BIO 394 Special Topics
BIO 492 Honors Directed Study
BIO 498 Pro-Seminar
Spring 2019
Course Number Course Title
BIO 302 Cancer-Mother of All Diseases
BIO 394 Special Topics
BIO 492 Honors Directed Study
Fall 2018
Course Number Course Title
BIO 302 Cancer-Mother of All Diseases
Spring 2018
Course Number Course Title
BIO 302 Cancer-Mother of All Diseases
BIO 493 Honors Thesis
BIO 591 Seminar
Fall 2017
Course Number Course Title
BIO 302 Cancer-Mother of All Diseases
Spring 2017
Course Number Course Title
BIO 302 Cancer-Mother of All Diseases
BIO 591 Seminar

Presentations

  • Compton CC. Biospecimens, Biomarkers and Genomics: Whats the Issue and Why Does It Matter?. NBDA Convergence Conference on Genomics (Dec 2014).
  • Compton CC. Biospecimens, Biomarkers and Proteomics: Whats the Issue and Why Does It Matter. NBDA Convergence Conference on Proteomics (Dec 2014).
  • Compton CC. Perspectives on Tissue Management Issues for Pathologist when Sending Tissue for Genomic Testing. College of American Pathologists Personalized healthcare Committee Meeting (Nov 2014).
  • Compton CC. Challenge, Convergence, Complexity and Change in Cancer Care: Are We Ready?. American College of Surgeons Annual Meeting (Oct 2014).
  • Compton CC. Biospecimens and Biomarkers: What Will It Take to Get to Precision Medicine?. World Congress on Skin Cancer (Sep 2014).
  • Compton CC. Biobanking and Precision Medicine for Cancer. Leaders in Biobanking Congress (Sep 2014).
  • Compton CC. The Right Stuff for Translational Biomedical Research: Garbage In, Garbage Out. Embracing Change: Enhancing Clinical Research Practices Conference (Sep 2014).
  • Compton CC. The Crisis in Biomarker Development for Cancer: What Will It Take to Get to Precision Medicine?. Annual Research Day, University of Dundee, Scotland (Sep 2014).
  • Compton CC. Leveraging Genomics In Oncology Clinical Development: Current And Future Benefits And Challenges. ASCO Annual Meeting (May 2014).
  • Compton CC. Technology Development, Disruptive Innovation and the Future of Oncology. American radium Society Annual Meeting (Apr 2014).
  • Compton CC. Accelerated FDA Approvals: What the Future Holds". CED Life Sciences Conference, Raleigh, SC (Feb 2014).

Honors/Awards

Aesulapian Society  Harvard Medical School 1972

Presidents Award  College of American Pathologist 2000

Frank W. Harman Award  College of American Pathologists 2003

Award of Merit  NIH (Group award for the Biorepository Coordinating Committee  chaired by Dr. Compton) 2006

Award of Merit  NIH (Group award for the Biorepository and Biospecimen Research  directed by Dr. Compton) 2006

Americas Top Physicians  Consumers Research Council of Americ 2007

Americas Top Pathologists  Consumers Research Council of America 2007

Americas Top Pathologists  Consumers Research Council of America 2008

Americas Top Pathologists  Consumers Research Council of America 2009

NIH Directors Award  - NIH Group Award for the NCI Community Cancer Centers Program 2009

Americas Top Pathologists  Consumers Research Council of America 2010

NIH Directors Award  - NIH Group Award for the NCI Community Cancer Centers Program 2011

NIH 2011 Gold Plain Language/Clear Communication Award  - NIH 2011

 

Honorary Director Tissue Bank Consortium of Asia  - Tissue Bank Consortium of Asia 2011

ISBER Award for Outstanding Achievement in Biobanking 2011

Women of Influence  - Tucson, AZ

Pathology Power List  Top 100 pathologists of 30,000 worldwide

AACR Team Science Award

CFA Culling Memorial Lecture Award, National Society for Histopathology

ASU SUN (Serving University Needs) Award 2012, 2015 and 2016, 2020
 

Outstanding Medical Educator of the Year  University of Massachusetts Medical School

Outstanding Medical Educator of the Year  University of Massachusetts Medical School

Faculty Prize for Excellence in Teaching  Harvard Medical School

Faculty Prize for Excellence in Teaching  Harvard Medical School

 

 

 

Editorships

Biopreservation and Biobanking Editorial Board

Journal of Molecular Nanotechnology and Nanomedicine Editorial Board

Immunome Research Journal Editorial Board

          Gastrointestinal Cancer: Research and Therapy Editorial Board

          Pharmacogenomics and Personalized Medicine Editorial Board

          Extracellular Vesicles and Circulating Nucleic Acids Editorial Board

 

Professional Associations

American Joint Committee on Cancer, Executive Committee

College of American Pathologists, Chair, Preanalytics for Precision Medicine Project Team

American Association of Cacer Research, Pathology Committee

Blood Profilig Atlas in Cancer (BloodPAC), CAP representative

 

 

Service

  • Volitile Organic Compinds project of the Physical Sciences Oncology Centers program at the NCI, Scientific Advisor (2103 - 2021)
  • Member Nominating Committee, American Joint Committee on Cancer Chair,, Chair (2013 - 2021)
  • Feed My Starving Children, Faculty Sponsor (2013 - 2021)
  • Precision Medicine Core Committee, American Joint Committee on Cancer, Chiar (2013 - 2021)
  • American Joint Committee on Cancer, 8th Edition Cancer Staging Manual, Editorial Board (2012 - Present)
  • International Union for Cancer Control, TNM Committee, USA AJCC representative and member (2008 - 2020)
  • Accreditation Committee, Commission on Cancer, American College of Surgeons, Member (2008 - 2018)
  • Institute of Medicine, National Academy of Sciences, Expert Reviewer for IOM study: Management of The Air Force Health Study Data and Specimens - Report to Congress (2014 - 2014)
  • HealthTell, Board of Directors (2014 - 2014)
  • American Joint Committee on Cancer, Editorial Board of the 8th Edition of the Cancer Staging Manual (2014 - 2014)
  • American Joint Committee on Cancer, Executive Committee (2014 - 2014)
  • Commission on Cancer, American College of Surgeons, Executive Committee member (2014 - 2014)
  • Complex adaptive Systems Initiative, Chief Medical Officer (2014 - 2014)
  • Feed My Starving Children, Faculty Sponsor (2014 - 2014)
  • Indivumed GMBH, scientific consultant (2014 - 2014)
  • International Union for Cancer Control, USA representative to the TNM Staging Committee (2014 - 2014)
  • National Biomarker Development Alliance, Chief Medical Officer (2014 - 2014)
  • Precision Medicine Core of the American Joint Committee on Cancer, Chair (2014 - 2014)
  • Sun Devils for Public Health, Faculty Sponsor (2014 - 2014)
  • National Human Genome Research Institute, Expert Advisory Panel (2014 - 2014)
  • Summer Bridge Program, Lecturer/instrictor (2014 - 2014)
  • Clinical Data Interchange Standards Consortium, Board of Directors (2012 - 2013)
  • American Joint Committee on Cancer, Chairman (2008 - 2013)

Graduate Faculties / Mentoring History

At ASU:

Chair, ASU PhD Thesis Committee: Eric Woolf

Faculty Advisor: ASU Chapter, American Womens Medical Association

Faculty Advisor: ASU Chapter, Feed My Starving Children

Faculty Advisor: ASU Chapter, Stand Up To Cancer

PhD Thesis Committee  James Abraham

 

Faculty Director: The Making of a COVID Lab

Multidisciplinary Team Barrett Honors Project

Documentary Video: https://youtu.be/QKoko2QZIMM

PBS: https://azpbs.org/horizon/2021/06/asu-lab-stepped-up-to-help-az-through-the-pandemic/

Book

Work History

Assistant Professor of Pathology  University of Massachusetts Medical School

Staff Pathologist and Acting Chief  Hospital Pathology, Department of Pathology, University of Massachusetts Medical Center

Director  Surgical Pathology, Autopsy Pathology, Residency Program, University of Massachusetts Medical Center

Assistant Professor of Medicine  University of Massachusetts Medical School, Worchester, MA

Assistant Pathologist  Department of Pathology, Massachusetts General Hospital, Boston, MA

Assistant Professor of Pathology  Harvard Medical School, Boston, MA

Chief of Gastrointestinal Pathology  Department of Pathology, Massachusetts General Hospital, Boston, MA

Assistant Histochemist  Department of Surgery, Massachusetts General Hospital, Boston, MA

Assistant Pathologist  Department of Pathology, Shriners Burns Hospital, Boston, MA

Associate Histochemist  Department of Surgery, Massachusetts General Hospital, Boston, MA

Associate Pathologist  Department of Pathology, Massachusetts General Hospital, Boston, MA

Associate Pathologist  - Department of Pathology, Shriners Burns Hospital, Boston, MA

Associate Professor of Pathology  Harvard Medical School, Boston, MA

Pathologist  Department of Pathology, Massachusetts General Hospital, Boston, MA

Pathologist  Department of Pathology, Shriners Burns Hospital, Boston, MA

Histochemist  Department of Surgery, Massachusetts General Hospital, Boston, MA

Pathologist-in Chief, Director of Laboratories  Department of Pathology, Shriners Burns Hospital, Boston, MA

Consultant in Gastrointestinal Pathology  National Cancer Institute, Bethesda, MD

Professor of Pathology  Harvard Medical School, Boston, MA

Member/Pathologist  Dana Farber  Harvard Cancer Center

Professor of Oncology  Department of Oncology, McGill University, Montreal, Quebec, Canada

Strathcona Professor and Chairman  Department of Pathology, McGill University, Montreal, Quebec, Canada

Pathologist-in-Chief  McGill University Health Center, Montreal, Quebec, Canada

Director of Office of Biorepositories and Biospecimen Research - National Cancer Institute, Office of the Director

Pathologist  Department of Pathology, National Cancer Institute Clinical Center

Acting Director  Office of Technology and Industrial Relations, National Cancer Institute, Bethesda, MD

Executive Director  The Cancer Human Biobank, (caHUB�), National Cancer Institute, Bethesda, MD

Adjunct Professor of Pathology, Johns Hopkins School of Medicine

CEO and President  Critical Path Institute

CMO - National Biomarker Development Alliance

CMO  Complex Adaptive Systems Institute, ASU

Professor of Laboratory Medicine and Pathology, Mayo Clinic School of Medicine

Affiliated Scholar  ASU Center for Health Care Delivery and Policy

Honorary Professional Fellow, Queen Mary University London - Barts Hopsital

 

                    

Expertise Areas