Christos Katsanos

Mayo Clinic Collaborative Research Building, Rm 2-223
13208 East Shea Boulevard
Scottsdale
Associate Professor
Faculty
TEMPE Campus
Mailcode
4501

Biography

Christos Katsanos is an exercise physiologist who studies metabolic responses in human obesity. His laboratory utilizes infusion of molecules labeled with stable isotopes in combination with tissue biopsies to investigate metabolic responses, in vivo. These methodologies are complemented by mass spectrometry analytical techniques as well as molecular biology techniques that provide novel approaches in gaining a comprehensive understanding of substrate metabolism in skeletal muscle of human subjects.

The current focus of his research is on metabolic abnormalities developed in skeletal muscle secondary to obesity. He is specifically interested in how muscle metabolic responses related to protein and fat metabolism are altered in obese humans, and how abnormal responses related to the metabolism of these substrates in muscle of people with obesity can be favorably altered by exercise and dietary interventions.

Education

  • PhD Florida State University 2001
  • MS University of Louisville 1998

Publications

Tran L, Hanavan PD, Campbell LE, De Filippis E, Lake DF, Coletta DK, Roust LR, Mandarino LJ, Carroll CC, Katsanos CS. "Prolonged Exposure of Primary Human Muscle Cells to Plasma Fatty Acids Associated with Obese Phenotype Induces Persistent Suppression of Muscle Mitochondrial ATP Synthase β Subunit". PLoS One 11(8):e0160057. doi: 10.1371/journal.pone.0160057, 2016.

Everman S, Meyer C, Tran L, Hoffman N, Carroll CC, Dedmon WL, Katsanos CS. "Insulin does not stimulate muscle protein synthesis during increased plasma branched-chain amino acids alone but still decreases whole body proteolysis in humans". Am J Physiol Endocrinol Metab 311(4):E671-E677, 2016.

Kras KA, Willis WT, Barker N, Czyzyk T, Langlais PR, Katsanos CS." Subsarcolemmal mitochondria isolated with the proteolytic enzyme nagarse exhibit greater protein specific activities and functional coupling". Biochem Biophys Rep 6:101-107, 2016.

Tran L, Masters H, Roust LR, Katsanos CS. "A new method to measure muscle protein synthesis in humans by endogenously introduced d9-leucine and using blood for precursor enrichment determination". Physiol Rep Aug;3(8). pii: e12479. doi: 10.14814/phy2.12479, 2015.

Everman S, Mandarino LJ, Carroll CC, Katsanos CS. " Effects of acute exposure to increased plasma branched-chain amino acid concentrations on insulin-mediated plasma glucose turnover in healthy young subjects". PLoS One 10(3):e 0120049. doi: 10.1371/journal.pone. 0120049, 2015.

Puga GM, Meyer C, Mandarino LJ, Katsanos CS. "Increased plasma availability of L-arginine in the postprandial period decreases the postprandial lipemia in older adults". Nutrition 29(1):81-88, 2013.

Puga GM, Meyer C, Mandarino LJ, Katsanos CS. "Postprandial spillover of dietary lipid into plasma is increased with moderate amounts of ingested fat and is inversely related to adiposity in healthy older men". J Nutr 142(10):1806-1811, 2012.

Everman S, Yi Z, Langlais P, Mandarino LJ, Luo M, Roberts C, Katsanos CS. "Reproducibility of an HPLC-ESI-MS/MS method for the measurement of stable-isotope enrichment of in vivo-labeled muscle ATP synthase beta subunit". PLoS One 6(10):e26171. doi:10.1371/journal.pone.0026171, 2011.

Puga GM, Meyer C, Everman S, Mandarino LJ, Katsanos CS. "Postprandial lipemia in the elderly involves increased incorporation of ingested lipid in plasma free fatty acids and small (Sf 20-400) triglyceride-rich lipoproteins". Am J Physiol Endocrinol Metab 301(2):E356-E361, 2011.

Courses

Fall 2018
Course Number Course Title
BIO 182 General Biology II
BIO 492 Honors Directed Study
BIO 494 Special Topics
BIO 495 Undergraduate Research
BIO 598 Special Topics
Summer 2018
Course Number Course Title
BIO 495 Undergraduate Research
Spring 2018
Course Number Course Title
BIO 495 Undergraduate Research
Fall 2017
Course Number Course Title
BIO 182 General Biology II
BIO 494 Special Topics
BIO 598 Special Topics
Summer 2017
Course Number Course Title
BIO 495 Undergraduate Research
Fall 2016
Course Number Course Title
BIO 181 General Biology I
BIO 189 Life Sciences Career Paths
BIO 494 Special Topics
BIO 598 Special Topics
Summer 2016
Course Number Course Title
BIO 495 Undergraduate Research
Fall 2015
Course Number Course Title
BIO 181 General Biology I
BIO 494 Special Topics
BIO 598 Special Topics
Summer 2015
Course Number Course Title
BIO 495 Undergraduate Research
Fall 2014
Course Number Course Title
BIO 181 General Biology I
BIO 494 Special Topics
BIO 598 Special Topics
Summer 2014
Course Number Course Title
BIO 495 Undergraduate Research
Spring 2014
Course Number Course Title
BIO 495 Undergraduate Research