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Dr Lukas's work focuses on nicotinic acetylcholine receptors, which are relevant to a number of neurological and other diseases, in addition to their roles in nicotine dependence and tobacco-related diseases.
Structure, funciton, pharmacology and other interactions with nicotinic acetcylcholine receptors. Drug discovery. Roles for nicotinic receptors in nicotine dependence, neurodegenerative and neuroinflammatiry diseases. Nicotinic receptors in stroke, Alzherimers disease, Parkinsons disease, epilepsy, multiple sclerosis, depression, anxiety, attention deficit disorder, schizophrenia. Nicotinic receptors in the nervosu system, but also at the neuromuscular juntion and in the immune system.